Mood Disorders
Posted: Monday, May 16, 2005
by Dr Virgil Davis
MOOD DISORDERS
We have all experienced depression on occasion, as a natural response to setbacks such as failing an exam, ending a relationship, or being rejected by a potential employer. Fortunately for most of us, depression is a transitory state that generally lifts in short order as life goes on. However, when feelings of sadness, dejection, and hopelessness persist longer than a few weeks and when these feelings are severe enough to disrupt everyday functioning, the depression is considered to be an abnormal behavioral state.
The common symptoms or signs of depression include a variety of psychological, psychomotor, and physical manifestations, such as severe and prolonged feelings of sadness, hopelessness, and despair low self-esteem a sense of worthlessness eating disturbances (either undereating or overeating) sleep disturbances (either insomnia or excessive sleep) psychomotor disturbances characterized by a marked shift in activity level a variety of somatic or bodily complaints lack of energy with accompanying fatigue loss of interest in and enjoyment of everyday activities indecisiveness difficulty in concentrating and persistent thoughts of suicide and death.
Like anxiety, depression is associated with many varieties of behavioral disorders, including the anxiety and somatoform disorders, substance-related disorders such as alcoholism, and schizophrenia, which we discuss later in this chapter. In these and related conditions, depression is secondary to other symptoms. In contrast, depression is the primary problem in the mood disorders.
DSM-IV distinguishes two major mood disorders: major depressive disorder and bipolar disorder. A major depressive episode is characterized by depressed mood, diminished interest in activities, significant weight loss or gain, sleep disturbances, restlessness, fatigue, diminished ability to concentrate, and/or recurrent thoughts of suicide. In addition, some or all of these symptoms must be severe enough to impair social or occupational functioning.
Bipolar disorder (sometimes called manic depression) is characterized by intermittent episodes of mania, or periods of both depression and mania. Mania is a highly energized state characterized by an inflated self-esteem, decreased need for sleep, increased pressure to talk, racing thoughts, distractibility, and/or increases in directed activity. These symptoms, as well as those for the depressive episode, must be severe enough to impair social or occupational functioning to warrant the diagnosis of bipolar disorder.
The distinction between major depressive disorder and bipolar disorder is an important one that is based on different symptomatology as well as different etiology. Bipolar disorder generally appears during a person’s twenties, whereas major depressive disorder is more likely to develop later, often in a person’s thirties. However, major depressive disorder may occur in children, adolescents, or young adults, and recent research provides evidence of an increased rate in younger people (American Psychiatric Association, 2003). Symptoms of depression may vary somewhat according to the disorder. The depression associated with bipolar disorder typically causes a person to become lethargic and sleep more. In contrast, major depressive disorder is characterized by insomnia and agitation. These two different types of mood disorders also respond quite differently to various treatments.
As many as one out of five Americans may experience a severe depressive episode at some point in time, but only 1 percent of the population will be diagnosed with bipolar disorder (Davison & Neale, 1990). Evidence suggests that the incidence of mood dis-orders has been progressively increasing over the last few decades. It is now estimated that 19 million people in the United States suffer from depression severe enough to interfere with their life and depression is now the leading cause of disability in the United States and worldwide (National Institute of Mental Health, 2003).
Major Depressive Disorder
People diagnosed as having major depressive disorder typically manifest their symptoms over an extended period, from several months to a year or longer, and their ability to function effectively may be so impaired that hospitalization is warranted. The following brief case study illustrates some of the common symptoms of severe depression:
Not surprisingly, people with major depressive disorder almost inevitably experience a breakdown in interpersonal relationships. Most of us do not enjoy being around irritable people, and since many depressed people are irritable, it is understandable that friends, associates, and even family members may eventually gravitate away from such people. In addition, depressed people often seek guidance and support from others, and it can be very frustrating for friends to observe that their efforts to provide help often seem to have no effect. Sometimes people may avoid depressed individuals because such interactions often make them feel gloomy or depressed.
Although often incapacitating and sometimes even life threatening (individuals who contemplate suicide are often deeply depressed), episodes of major depression are generally transitory in nature. In most cases the depression lifts over a period of months, regardless of whether or not it is treated. However, most people with diagnosed major depressive disorder experience one or more recurrence(s) of major depression later on in their lives.
Bipolar (Manic-Depressive) Disorder
In contrast to major depressive disorder, bipolar disorder is characterized by extreme mood swings. In some cases, periods of mania recycle while in other cases episodes of depression and elation may alternate, with months or years of symptom-free normal functioning between the disordered mood states. Other cases may be characterized by a series of intermittent manic episodes followed by a period of depression. Unlike the normal highs and lows most of us experience in response to life events, the depression and mania associated with bipolar disorder do not seem to be triggered by identifiable events. In some manic-depressives, depressive symptoms may occur concurrently with classic manic features, a condition referred to as mixed mania.
About one in 100 people suffer from bipolar disorder, a rate comparable to that of schizophrenia but far lower than the incidence of major depression. Men and women are equally likely to develop bipolar disorder. Since the depression experienced in bipolar disorder is quite similar to what we already described as experienced in major depression (with noteworthy differences in sleep and activity level), we focus here on the manic symptoms of the disorder.
According to DSM-IV, manic episodes are characterized by "inflated self-esteem or grandiosity (which may be delusional), decreased need for sleep, pressure of speech, flight of ideas, distractibility, increased involvement in goal-directed activity, psychomotor agitation, and excessive involvement in pleasurable activities that have a high potential for painful consequences that the person often does not recognize." Manic episodes often begin suddenly and escalate rapidly, as revealed in the following case:
The following bit of conversation from the period after Mr. M. entered treatment indicates his incorrigible optimism and provocativeness.
Therapist: Well, you seem pretty happy today.
Client: Happy! Happy! You certainly are a master of understatement, you rogue! (shouting, literally jumping out of his seat). Why I’m ecstatic, I’m leaving for the West Coast today, on my daughter’s bicycle. Only 3,100 miles. That’s nothing, you know. I could probably walk, but I want to get there by next week. And along the way I plan to contact a lot of people about investing in my fish equipment. I’ll get to know more people that way-you know, Doc, "know" in the biblical sense (leering at therapist seductively). Oh, God, how good it feels. (Davison & Neale, 1986, p. 196)
Table 1 Suicide Facts
2. For every successful suicide there are at least 8 to 25 attempts. This translates to approximately a quarter of a million suicide attempts each year in this country.
3. Four times more men than women succeed in committing suicide, although over three times as many women as men attempt suicide. Men often use absolute and irreversible methods, such as guns and hanging, to kill themselves, whereas women are more likely to use drugs, gas, or poison.
4. Suicide rates by age group rise steadily from adolescence to the elderly. The highest rates are for white men over 85.
5. About 80 percent of people who kill themselves provide ample verbal or other behavior clues beforehand.
6. It is believed that more than half of the people who commit suicide are seriously depressed at the time of the act. However, many people who kill themselves do not have a diagnosable psychological disorder.
SOURCES: National Institute of Mental Health, 2003
 
Episodes of either mania or depression tend to last only a few weeks or months. When they lift, the person recovers and returns to a symptom-free life. Unfortunately, however, the symptoms tend to recur, and many people require periodic treatment and sometimes maintenance medication throughout their lives. This pattern takes its toll in the form of alienated friends and loved ones, financial problems, and careers that remain on hold due to the unpredictable nature of symptoms. One of the most devastating aspects of this disorder is the high risk of suicide associated with it (see Table 1). Available evidence indicates that people with bipolar disorders are more likely to kill themselves than any other group of people with a behavioral disorder.
 
 
 
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Top-level comments on this article: (1 total)I would like to say that is a interesting article and you did a great job. Glad to know that you also share your knowledge with more than just your students.
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